Thomas MacCarthy Selected Research

AICDA (activation-induced cytidine deaminase)

1/2017	The Number of Overlapping AID Hotspots in Germline IGHV Genes Is Inversely Correlated with Mutation Frequency in Chronic Lymphocytic Leukemia.
12/2012	IGHV-unmutated and IGHV-mutated chronic lymphocytic leukemia cells produce activation-induced deaminase protein with a full range of biologic functions.

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Thomas MacCarthy Research Topics

Disease

4	Infections 01/2021 - 04/2013
4	Neoplasms (Cancer) 10/2020 - 11/2015
3	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 01/2017 - 12/2012
2	Burkitt Lymphoma (Burkitt's Lymphoma) 01/2021 - 01/2011
1	Genomic Instability 10/2018
1	Carcinogenesis 11/2015
1	Squamous Cell Carcinoma of Head and Neck 11/2015
1	Cardiovascular Diseases (Cardiovascular Disease) 08/2007

Drug/Important Bio-Agent (IBA)

3	Proteins (Proteins, Gene)FDA Link 01/2021 - 12/2012
2	Immunoglobulins (Immunoglobulin)IBA 01/2017 - 04/2013
2	AICDA (activation-induced cytidine deaminase)IBA 01/2017 - 12/2012
1	MethyltransferasesIBA 01/2021
1	CytidineIBA 01/2021
1	Single-Stranded DNA (DNA, Single Stranded)IBA 01/2021
1	Pharmaceutical PreparationsIBA 10/2020
1	RNA (Ribonucleic Acid)IBA 01/2019
1	DNA (Deoxyribonucleic Acid)IBA 10/2018
1	CarcinogensIBA 11/2015
1	Messenger RNA (mRNA)IBA 11/2015
1	MicroRNAs (MicroRNA)IBA 11/2015
1	EpitopesIBA 04/2013
1	Biological ProductsIBA 12/2012
1	Recombinases (Recombinase)IBA 01/2011
1	Cholesterol Ester Transfer ProteinsIBA 08/2007
1	Lipoproteins (Lipoprotein)IBA 08/2007

Therapy/Procedure

1	Heterologous Transplantation (Xenotransplantation) 04/2016